Ayakulik River starts at an unnamed lake about 2.5 miles (4 km) east of Grant Lagoon on the southwest coast of Kodiak Island and it flows generally south for 30 miles (48 km) to the southern flank of Mount Myrtle on the Shelikof Strait coast where the historical village of Ayakulik was located, about 89 miles (143 km) southwest of Kodiak and 22 miles (35 km) northwest of Akhiok, Alaska.